#1 Project MKUltra
MKUltra was launched in the 1950s by the CIA. It was aimed at finding the right method to render mind control. The CIA started with electrical shock, sleep deprivation, and hallucinogens and conducted their experiments on nonvolunteer subjects. One of their research projects required slipping LSD into the drinks of bar patrons in San Francisco and New York, without them knowing. However, the project was limited in 1964, stopped in 1967, and officially ended in 1973.